Early Insights From a Pharmacogenomic-Enriched Comprehensive Medication Management Program Implementation in an Adult Employee Population. Issue 12 (22nd December 2022)

• Record Type: Journal Article
• Authors: Keogh, Murray; Fragala, Maren S.; Peter, Arul Prakasam; Lorenz, Raymond A.; Goldberg, Steven E.; Shaman, Jeffrey A.
• Is Part Of: Journal of occupational and environmental medicine. Volume 64:Issue 12(2022)
• Page Start: e818
• Page End: e822
• Publication Date: 2022-12-22
• Subjects: adverse drug reactions -- employee health -- employer health costs -- medication management -- medication safety -- personalized medicine -- pharmacogenetics -- polypharmacy; Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; Occupational Medicine -- Periodicals; Environmental Medicine -- Periodicals; Environmental health; Medicine, Industrial; Periodicals; Electronic journals; 616.9803
• DOI: 10.1097/JOM.0000000000002705
• Languages: English
• ISSNs: 1076-2752

Abstract

Abstract : A pharmacogenomics-enriched comprehensive medication management program that includes pharmacists empowered with pharmacogenomic data and a clinical decision support tool can detect risks in prescription regimens that are prevalent in an employee population and offers opportunities to improve medication management. Abstract : Objectives: The aims of the study are to assess adoption of a pharmacogenomic-enriched comprehensive medication management program in a self-insured employer setting and to better understand medication risks that affect employees. Methods: Employees were identified to be at high risk of medication mismanagement and were subsequently provided with a program and process to improve their health. DNA testing, a clinical decision support system, and pharmacists were used to identify medication safety and effectiveness issues and to recommend appropriate changes. Results: A total of 10.6% of the invited employees enrolled in the program. Actionable recommendations were suggested by pharmacists for 85.8% of employees who completed the program, averaging 5.2 recommendations per person. Conclusions: Implementation of a PGx + CMM program in a self-insured employer setting is feasible, detects risks in prescription regimens, and offers opportunities to improve medication management and reduce the burden of healthcare expenses.