Inflammation—Cause or consequence of late onset Alzheimer's disease or both? A review of the evidence. (May 2022)

• Record Type: Journal Article
• Authors: Zhao, Jinrong; Zhao, Dong; Wang, Jinpei; Luo, Xiaoe; Guo, Rui
• Is Part Of: European journal of inflammation. Volume 20(2022)
• Publication Date: 2022-05
• Subjects: Alzheimer's disease -- inflammation -- risk factors -- amyloid-β; Inflammation -- Periodicals; Anti-Inflammatory Agents -- therapeutic use -- Periodicals; Immunotherapy -- Periodicals; Inflammation -- Periodicals; Anti-inflammatory agents -- Periodicals; Immunotherapy -- Periodicals; Anti-inflammatory agents; Immunotherapy; Inflammation; Periodicals; 616.0473
• DOI: 10.1177/1721727X221095383
• Languages: English
• ISSNs: 1721-727X

Abstract

Accumulating evidence suggests that inflammation is involved in the development of late onset Alzheimer's disease (LOAD). However, it is not clear whether inflammation is a cause or consequence, or both. The aim of this paper is to review the relationship between inflammation and LOAD. We also review the effect of anti-inflammation on the risk of LOAD to further elucidate the relationship between inflammation and LOAD.