Treatment Effects in Prostate Cancer following Traditional and Emerging Therapies. (April 2013)

• Record Type: Journal Article
• Authors: Mazzucchelli, R.; Scarpelli, M.; Lopez-Beltran, A.; Cheng, L.; Di Primio, R.; Montironi, R.
• Is Part Of: International journal of immunopathology and pharmacology. Volume 26:Number 2(2013)
• Page Start: 291
• Page End: 298
• Publication Date: 2013-04
• Subjects: prostate cancer -- treatment effects; Immunopathology -- Periodicals; Pharmacology -- Periodicals; Inflammation -- Periodicals; 615.1
• DOI: 10.1177/039463201302600202
• Languages: English
• ISSNs: 0394-6320

Abstract

Treatment options for prostate cancer consist of radical prostatectomy, hormonal therapy and radiation therapy. Hormonal and radiation therapy have well-known, often profound, effects on the histological appearance of benign and malignant prostate tissue. Novel therapies including focal ablative treatments, chemotherapies and targeted molecular therapies are beginning to emerge and pathologists will play a central role in documenting the effects of these treatments at the tissue level. As such, knowledge of treatment-related changes and access to clinical information are essential to ensure accurate interpretation and reporting of post-treatment prostate specimens by pathologists.