Retrograde tibiotalocalcaneal nailing for the treatment of acute ankle fractures in the elderly: a systematic review and meta-analysis. Issue 9 (19th September 2022)

• Record Type: Journal Article
• Authors: Lu, Victor; Tennyson, Maria; Zhou, Andrew; Patel, Ravi; Fortune, Mary D; Thahir, Azeem; Krkovic, Matija
• Is Part Of: EFORT open reviews. Volume 7:Issue 9(2022)
• Page Start: 628
• Page End: 643
• Publication Date: 2022-09-19
• Subjects: ankle fracture -- tibiotalocalcaneal nailing -- fragility fracture -- ORIF -- meta-analysis; Orthopedics -- Periodicals; Musculoskeletal system -- Periodicals; Musculoskeletal system -- Wounds and injuries -- Periodicals; 616.7
• DOI: 10.1530/EOR-22-0017
• Languages: English
• ISSNs: 2058-5241

Abstract

Abstract : Introduction: Fragility ankle fractures are traditionally managed conservatively or with open reduction internal fixation. Tibiotalocalcaneal (TTC) nailing is an alternative option for the geriatric patient. This meta-analysis provides the most detailed analysis of TTC nailing for fragility ankle fractures. Methods: A systematic search was performed on MEDLINE, EMBASE, Cochrane Library, and Web of Science, identifying 14 studies for inclusion. Studies including patients with a fragility ankle fracture, defined according to NICE guidelines as a low-energy fracture obtained following a fall from standing height or less, that were treated with TTC nail were included. Patients with a previous fracture of the ipsilateral limb, fibular nails, and pathological fractures were excluded. This review was registered in PROSPERO (ID: CRD42021258893). Results: A total of 312 ankle fractures were included. The mean age was 77.3 years old. In this study, 26.9% were male, and 41.9% were diabetics. The pooled proportion of superficial infection was 10% (95% CI: 0.06–0.16), deep infection 8% (95% CI: 0.06–0.11), implant failure 11% (95% CI: 0.07–0.15), malunion 11% (95% CI: 0.06–0.18), and all-cause mortality 27% (95% CI: 0.20–0.34). The pooled mean post-operative Olerud–Molander ankle score was 54.07 (95% CI: 48.98–59.16). Egger's test ( P = 0.56) showed no significant publication bias. Conclusion: TTC nailing is an adequate alternative option for fragility ankle fractures. However, current evidence includes mainly case series with inconsistent post-operative rehabilitation protocols. Prospective randomised control trials with long follow-up times and large cohort sizes are needed to guide the use of TTC nailing for ankle fractures.