A comparative analysis of the efficacy of anterior cruciate ligament reconstruction with autologous ligament grafting at different time points. Issue 12 (26th August 2020)

• Record Type: Journal Article
• Authors: Hu, Bo; Gao, Feng; Li, Chunbao; Zhang, Boqing; An, Mingyang; Lu, Ming; Liu, Yufeng; Liu, Yujie
• Is Part Of: Journal of clinical laboratory analysis. Volume 34:Issue 12(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-08-26
• Subjects: ACL injury -- knee joint function -- operation timing -- QOL -- reconstruction with autologous ligament grafting -- stability; Diagnosis, Laboratory -- Periodicals; Medical laboratory technology -- Periodicals; 616
• DOI: 10.1002/jcla.23543
• Languages: English
• ISSNs: 0887-8013

Abstract

Abstract: Background: This study was performed to compare the clinical efficacies of anterior cruciate ligament (ACL) reconstruction with autologous ligament grafting at different time points. Methods: Eighty‐five patients with ACL were categorized into two groups: Group A (GA, n = 45), who underwent early‐stage (≤3 weeks) surgery, and Group B (GB, n = 40), who underwent advanced‐stage (>3 weeks) surgery. Perioperative conditions, knee joint functions, activity and stability before and at 6 months postoperatively, changes in quality of life (QOL), good and excellent rates of knee joint functions, and incidence of complications were compared between the two groups. Results: In both groups, there was an increase in the International Knee Documentation Committee (IKDC) score, Lysholm score, and QOL and a decrease in the knee joint angle flexion limitation, angle of spread limitation, positive rates in the anterior drawer test (ADT), and Lachman test score ( P < .05) after surgery. At 6 months postoperatively, the IKDC score, Lysholm score, and QOL were higher in GA than in GB ( P < .05). The good and excellent rates of knee joint functions were higher in GA than in GB (93.33% vs. 77.50%) ( P < .05). Conclusion: Anterior cruciate ligament reconstruction with autologous ligament grafting can achieve good effects whether performed in the early or advanced stage; however, the improvements in patients' knee joint functions and QOL are better in the early stage. Therefore, early ACL reconstruction with autologous ligament grafting is suggested. Abstract : Intergroup comparison of perioperative conditions.