2022-RA-1235-ESGO Adult ovarian granulosa cell tumors: clinical and imaging findings characteristics of a Tunisian population sample. (20th October 2022)

• Record Type: Journal Article
• Authors: Bouhmida, Rahma; Souayeh, Nesrine; Chermiti, Amal; Bettaieb, Hajer; Ouederni, Meriem; Mbarki, Wael; Abidi, Idriss; Lamiri, Hadir; Rouiss, Hadhami; Oueslati, Hedhili; Mbarki, Chaouki
• Is Part Of: International journal of gynecological cancer. Volume 32(2022)Supplement 2
• Page Start: A312
• Page End: A312
• Publication Date: 2022-10-20
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2022-ESGO.665
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction/Background: Adult-type granulosa cell tumor (GCT) is a rare subtype of ovarian cancer. It derlves from sex cord stromal cells of the ovary. The incidence of GCTs is 0.6–0.8/100, 000, and it represents 3–5% of all ovarian malignancies. Methodology: a retrospective study concerning 40 cases of ovarian sex cord-stromal tumors (OSCST). Among them, we collected 17 cases of GCT. Epidemiological, clinical and radiological data were analyzed in this study. Results: GCT represented 42.5% of the OSCSTs and 1.15% of all ovarian tumors during the study period. The average age was 42.3 years . The mean parity of patients was 4. Menopausal average age calculated at 49 years . In 80% of cases patients were symptomatic; chronic pelvic pain 43.5%, meno-metrorrhagia 36.5%. For Three patients the tumor was discovered by chance: one during a caesarean scare and two during an ultrasonography for infertility. Physical exam revealed a palpable mass in 9 cases (52.9%). with an average size of 8 cm, and a solid consistency. On ultrasonography, we found a compartmentalized cystic tumor with vascularized partitions in color and pulse Doppler in 71.42% of cases . An effusion in the douglas has been described in 35.71% .The ultrasound study must incorporate the endometrium, in our study, the endometrium was hyperplastic in two cases. In CT we found a predominant cystic forms (53%) with variable contents .In MRI, in75% of cases we found a hyposignal with T2 weighting with a multilocular cystic appearance with solid components. Conclusion: The variability in the histological type globally and in the cellular arrangement particularly of granulosa tumors has helped to create a spectrum of radiological manifestations, whose good assimilation of their semiology will make it easier to pose the diagnosis before the surgery.