Validation of a method to determine transformation of chemicals in anaerobic liquid pig and cattle manure for the OECD test guideline programme. (January 2023)

• Record Type: Journal Article
• Authors: Berkner, Silvia; Anke, Julia Margaretha; Düring, Rolf-Alexander; Fiebig, Silke; Junker, Thomas; Hennecke, Dieter; Herrchen, Monika; Meinerling, Maria; Römbke, Jörg; Thiele-Bruhn, Sören; Topp, Edward; Völkel, Wolfgang; Walter-Rohde, Susanne
• Is Part Of: Chemosphere. Volume 312:Part 1(2023)
• Publication Date: 2023-01
• Subjects: OECD Test guideline programme -- Pharmaceuticals -- Biocides -- Transformation -- Manure -- Environmental risk assessment; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2022.137210
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: Manure is widely used as a fertilizer and applied to agricultural land. It may contain highly active chemicals like veterinary medicinal products or biocides, which enter into the environment by this pathway. This is recognized by several regulatory frameworks, however, a detailed method for examining the transformation of chemicals in manure was lacking. This article describes the validation of a method for studying the anaerobic transformation of chemicals in pig and cattle liquid manure. Different steps are covered with an emphasis on the validation ring test and the OECD (Organisation for Economic Cooperation and Development) process that led to the recent adoption of the method as OECD Test Guideline (TG) 320. Graphical abstract: Image 1 Highlights: A new OECD Test Guideline (TG 320 on) on anaerobic transformation of chemicals in liquid manure has been validated by an inter-laboratory ring test. This is the first report of the outcome of validation results for a simulation type OECD fate study design. a robust, reliable, repeatable and reproducible, standardized method is now available for the regulatory environmental risk assessment of veterinary pharmaceuticals, biocides and other chemicals.