2022-RA-1472-ESGO Comparison of the diagnostic accuracy of contrast-enhanced/DWI MRI & ultrasonography in the differentiation between benign & malignant myometrial tumors. (20th October 2022)

• Record Type: Journal Article
• Authors: Zamani, Narges; Najibi, Shaparak; Zamani, Fatemeh
• Is Part Of: International journal of gynecological cancer. Volume 32(2022)Supplement 2
• Page Start: A81
• Page End: A81
• Publication Date: 2022-10-20
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2022-ESGO.179
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Introduction/Background: Various modalities including ultrasonography and magnetic resonance imaging (MRI) have been developed as imaging technique for screening malignant myometrial tumors, but a few studies assessed the diagnostic value of these two techniques in differentiation of benign from malignant myometrial tumors that had been the main purpose of this study. Methodology: This cross-sectional study was performed on 63 women underwent surgery for intrauterine masses that were initially assessed using MRI and ultrasound before surgery at a tertiary hospital in Tehran from 2016 to 2020. Their MRI was reviewed by a reputable radiologist in the field. The findings of histopathological assessment were considered as the gold diagnostic standard. Results: The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI to detect sarcoma were revealed to be 94.6%, 92.3%, 94.6%, 92.3%, and 93.7% respectively. Ultrasonography had not preferable applicability to differentiate sarcoma from benign tumors with sensitivity, specificity, PPV, NPV and accuracy of 35.1%, 88.4%, 81.2%, 48.9%, and 57.1% respectively. The diagnostic performance of both modalities was not affected by baseline clinical conditions including pain, abnormal uterine bleeding and menopausal status. Conclusion: MRI but not ultrasonography can effectively differentiate benign from malignant myometrial tumors.