Atypical Fibroxanthoma Arising in a Scar of Discoid Lupus Erythematosus. Issue 5 (September 2014)

• Record Type: Journal Article
• Authors: De Francesco, Vincenzo; Errichetti, Enzo; Pegolo, Enrico; Stinco, Giuseppe
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 18:Issue 5(2014)
• Page Start: 353
• Page End: 355
• Publication Date: 2014-09
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.2310/7750.2013.13144
• Languages: English
• ISSNs: 1203-4754

Abstract

Background: Malignant change in the scars of discoid lupus erythematosus (DLE) is a well-known event. In most cases, tumors are of epithelial origin, particularly squamous cell carcinomas and, less frequently, basal cell carcinomas and keratoacanthomas. The onset of soft tissue sarcomas in a DLE scar is a very rare event, however, because only one case of malignant fibrous histiocytoma has been described in the literature. Objective: We describe the first documented report of atypical fibroxanthoma (AFX) arising in an old scar of DLE. Results: Although we cannot exclude an accidental association between AFX and DLE, our case emphasizes that patients with DLE may develop AFX in the context of an old scar. Conclusion: Our finding further underlines the importance of strict and long-term surveillance of people with DLE to identify and remove eventual tumors at an early stage.