Streptococcus pneumoniae: 'captain of the men of death' and financial burden. Issue 12 (2nd December 2022)
- Record Type:
- Journal Article
- Title:
- Streptococcus pneumoniae: 'captain of the men of death' and financial burden. Issue 12 (2nd December 2022)
- Main Title:
- Streptococcus pneumoniae: 'captain of the men of death' and financial burden
- Authors:
- Yesilkaya, Hasan
Oggioni, Marco R.
Andrew, Peter W. - Abstract:
- Abstract : Streptococcus pneumoniae may inhabit the upper respiratory tract of humans without causing harm but it also causes diseases with high morbidity and mortality. It has excellent adaptive capabilities thanks to its ability to shuffle its genetic content by acquiring and incorporating DNA from other bacteria and is highly competent for genetic transformation. Sugar sensing, cleavage and transport ensure its fitness and survival in the host, and intracellular survival in macrophages has been linked to virulence. The polysaccharide capsule and toxin pneumolysin are the most important virulence determinants. Polysaccharide-based vaccines provide protection against the serotypes represented in vaccine formulations.
- Is Part Of:
- Microbiology. Volume 168:Issue 12(2022)
- Journal:
- Microbiology
- Issue:
- Volume 168:Issue 12(2022)
- Issue Display:
- Volume 168, Issue 12 (2022)
- Year:
- 2022
- Volume:
- 168
- Issue:
- 12
- Issue Sort Value:
- 2022-0168-0012-0000
- Page Start:
- Page End:
- Publication Date:
- 2022-12-02
- Subjects:
- Streptococcus pneumoniae -- pneumococcal infections -- virulence -- genome
Microbiology -- Periodicals
579 - Journal URLs:
- https://www.microbiologyresearch.org/content/journal/micro ↗
- DOI:
- 10.1099/mic.0.001275 ↗
- Languages:
- English
- ISSNs:
- 1350-0872
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 24535.xml