Peutz–Jeghers syndrome complicated by gastric‐type cervical mucinous carcinoma and primary peritoneal carcinoma. Issue 10 (18th July 2021)

• Record Type: Journal Article
• Authors: Kotaka, Saki; Kanno, Kiyoshi; Yanai, Shiori; Omori, Masako; Andou, Masaaki
• Is Part Of: Journal of obstetrics and gynaecology research. Volume 47:Issue 10(2021)
• Page Start: 3732
• Page End: 3736
• Publication Date: 2021-07-18
• Subjects: gastric type -- high‐grade serous carcinoma -- mucinous carcinoma -- Peutz–Jeghers syndrome -- primary peritoneal carcinoma; Gynecology -- Periodicals; Obstetrics -- Periodicals; 618.1005
• DOI: 10.1111/jog.14944
• Languages: English
• ISSNs: 1341-8076

Abstract

Abstract: A 45‐year‐old multiparous woman with a STK11 mutation and a history of Peutz–Jeghers syndrome underwent radical hysterectomy and bilateral salpingo‐oophorectomy for a gastric‐type cervical mucinous carcinoma. Four and a half years later, blood tests revealed elevations in CEA and CA125 tumor marker levels, and computed tomography showed multiple calcifications in the peritoneum. Peritoneal dissemination was suspected, and a laparoscopic biopsy was performed. Histopathology showed a high‐grade serous carcinoma, and the patient was diagnosed with a metachronous stage IIIC primary peritoneal carcinoma. She had no BRCA1/2 mutation. After chemotherapy with docetaxel, carboplatin, and bevacizumab, she achieved complete remission.