Risk of mortality among inpatients with COVID‐19 and type 2 diabetes: National data from Kuwait. Issue 4 (10th July 2021)

• Record Type: Journal Article
• Authors: Al‐Ozairi, Ebaa; Brown, Rosemary; Hamdan, Yasmine; Alabdullah, Lulwa; Voase, Nia; Al Kandari, Jumana; Alsaeed, Dalal; Al Ozairi, Abdulla; Hasan, Amal; Al‐Mulla, Fahd; Katikireddi, Srinivasa Vittal; Gray, Stuart R.; Gill, Jason M. R.; Celis‐Morales, Carlos A.; Sattar, Naveed; Welsh, Paul
• Is Part Of: Endocrinology, diabetes & metabolism. Volume 4:Issue 4(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-07-10
• Subjects: COVID‐19 -- death -- diabetes; Endocrinology -- Periodicals; Diabetes -- Periodicals; Metabolism -- Periodicals; 616.4
• DOI: 10.1002/edm2.287
• Languages: English
• ISSNs: 2398-9238

Abstract

Abstract: Introduction: To investigate type 2 diabetes as a risk factor for COVID‐19 death following hospital admission in Kuwait. Methods: A retrospective cohort study using data from a central hospital that cared for all hospitalized COVID‐19 patients in Kuwait. We investigated the association between type 2 diabetes, with COVID‐19 mortality using multiply imputed logistic regression and calculated the population attributable fraction. Results: A total of 5333 patients were admitted with COVID‐19, of whom 244 died (4.6%). Diabetes prevalence was 24.8%, but 53.7% of those who died had diabetes. After adjusting for age, sex, ethnicity and other comorbidities, diabetes was associated with death (OR 1.70 [95% CI 1.23, 2.34]) and admission to the intensive care unit more than 3 days after initial admission (OR 1.78 [95% CI 1.17, 2.70]). Assuming causality, the population attributable fraction for type 2 diabetes in COVID‐19 death was 19.6% (95% CI 10.8, 35.6). Conclusion: Type 2 diabetes is a strong risk factor for COVID‐19 death in the Middle East. Given the high prevalence of type 2 diabetes in the Middle East, as well as many Western countries, the public health implications are considerable. Abstract : Type 2 diabetes is a strong risk factor for COVID‐19 death in the Middle East. Given the high prevalence of type 2 diabetes in the Middle East, as well as many western countries, the public health implications are considerable.