Trends in Risk‐Adjusted 28‐Day Mortality Rates for Patients Hospitalized with COVID‐19 in England. Issue 5 (5th February 2021)

• Record Type: Journal Article
• Authors: Jones, Simon; Mason, Neil; Palser, Tom; Swift, Simon; Petrilli, Christopher M; Horwitz, Leora I
• Is Part Of: Journal of hospital medicine. Volume 16:Issue 5(2021)
• Page Start: 290
• Page End: 293
• Publication Date: 2021-02-05
• Subjects: Hospital care -- Periodicals; Clinical medicine -- Periodicals; 610
• DOI: 10.12788/jhm.3599
• Languages: English
• ISSNs: 1553-5592

Abstract

Abstract : Early reports showed high mortality from coronavirus disease 2019 (COVID‐19). Mortality rates have recently been lower; however, patients are also now younger, with fewer comorbidities. We explored 28‐day mortality for patients hospitalized for COVID‐19 in England over a 5‐month period, adjusting for a range of potentially mitigating variables, including sociodemographics and comorbidities. Among 102, 610 hospitalizations, crude mortality decreased from 33.4% (95% CI, 32.9‐34.0) in March 2020 to 15.5% (95% CI, 14.1‐17.0) in July. Adjusted mortality decreased from 33.4% (95% CI, 32.8‐34.1) in March to 17.4% (95% CI, 11.3‐26.9) in July. The relative risk of mortality decreased from a reference of 1 in March to 0.52 (95% CI, 0.34‐0.80) in July. This demonstrates that the reduction in mortality is not solely due to changes in the demographics of those with COVID‐19.