Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer. Issue 10 (25th August 2021)

• Record Type: Journal Article
• Authors: Mohamed, Sandy; Fokdal, Lars; Assenholt, Marianne S.; Kallehauge, Jesper; Lindegaard, Jacob C.; Tanderup, Kari
• Is Part Of: Journal of applied clinical medical physics. Volume 22:Issue 10(2021)
• Page Start: 315
• Page End: 319
• Publication Date: 2021-08-25
• Subjects: cancer vulva -- daily CBCT -- groin edema -- image guided radiotherapy -- inguinal lymph node boost -- VMAT; Medical physics -- Periodicals; Clinical medicine -- Periodicals; Health Physics; Clinical Medicine; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; 610.153
• DOI: 10.1002/acm2.13372
• Languages: English
• ISSNs: 1526-9914

Abstract

Abstract: We aimed to evaluate the extent of groin edema and its dosimetric effect in boosted inguinal lymph nodes (LN) for vulvar cancer patients. The level of edema was determined in 10 patients treated with radical radiotherapy. A dosimetric evaluation of six LNs in the patient with the maximum level of edema was performed. The accumulated dose across CBCT fractions was acceptable for all six LNs (>94% of prescribed dose) even with the development of up to 13 mm of edema. The major contributor to fractional dose degradation was geographical displacement of the nodes. We suggest evaluation of edema on daily CBCT.