Mitochondrial cristae as insulated transformers of metabolic energy. (16th October 2019)

• Record Type: Journal Article
• Authors: Schlame, Michael
• Is Part Of: EMBO journal. Volume 38:Number 22(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-10-16
• Subjects: Molecular biology -- Periodicals; 572.805
• DOI: 10.15252/embj.2019103472
• Languages: English
• ISSNs: 0261-4189

Abstract

Abstract : The mitochondrial inner membrane consists of the inner boundary membrane and invaginations called cristae, which differ in protein composition and likely have distinct functions. In this issue of The EMBO Journal, Wolf et al (2019) report that the cristae carry a higher membrane potential than the intervening boundary membranes. Their data suggest electro‐chemical discontinuity among segments of the inner membrane, implying that individual cristae may operate with some degree of independence. Abstract : A new study reveals that individual cristae of the inner mitochondrial membrane act as primary carriers of the proton‐motive force and are functionally independent.