Melatonin as first‐line treatment for sleep disorders in Parkinson's disease?. Issue 4 (8th November 2021)

• Record Type: Journal Article
• Authors: Cox, Caitríona; Mackett, Alistair
• Is Part Of: Progress in neurology and psychiatry. Volume 25:Issue 4(2021)
• Page Start: 29
• Page End: 32
• Publication Date: 2021-11-08
• Subjects: Neurology -- Periodicals; Psychiatry -- Periodicals; Nervous system -- Periodicals; 616.805
• DOI: 10.1002/pnp.728
• Languages: English
• ISSNs: 1367-7543

Abstract

Abstract : Sleep disturbance has been reported in up to 88%–98% of Parkinson's disease patients; various sleep disorders can present even before motor symptoms. Rapid eye movement sleep behaviour disorder (RBD), which can lead to violent dream enactment behaviour, has a prevalence in Parkinson's disease of 20% to 50% but best management of the condition is unclear. Here, the authors consider whether melatonin is an effective pharmacological option to manage RBD.