Supramolecular [2]pseudo-rotaxane polymer containing blue anthracene donor guest and green naphthalimide acceptor host as a FRET-ON sensor for hydrogen sulfide detection. (December 2022)

• Record Type: Journal Article
• Authors: Gouda, Chinmayananda; Pham, Be-Nhi; Nhien, Pham Quoc; Cuc, Tu Thi Kim; Weng, Chang-Ching; Wu, Chia-Hua; Wu, Judy I.; Li, Yaw-Kuen; Lin, Hong-Cheu
• Is Part Of: Dyes and pigments. Volume 208(2023)
• Publication Date: 2022-12
• Subjects: Forster resonance energy transfer (FRET) -- [2]Pseudo-rotaxane -- Host-guest -- Hydrogen sulfide; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2022.110873
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: A supramolecular host-guest [2]pseudo-rotaxane polymer containing blue-emissive (λem = 425 nm) anthracene-based di-topic donor guest (AN-G ) and green-emissive (λem = 530 nm) napthalimide-based di-topic acceptor host (NP–H ) after hydrogen sulfide (HS − anion) detection in semi-aqueous media was developed in this study. Towards HS − detection, the bi-fluorophoric [2]pseudo-rotaxane polymer possessed the best FRET process in the THF/Water solution (60% H2 O, v/v), which was confirmed by TRPL measurements with the shortest lifetime of 1.1 ns and FRET efficiency of 81.7% in comparison with the longer lifetime of 6.0 ns for mono-fluorophoric [2]pseudo-rotaxane polymer analogue before detection of HS − . The 1:1 host–guest molar ratio and the formation of the [2]pseudo-rotaxane polymer can be further verified using 1 H NMR complexation and DOSY experiments. The effects of pH and temperature were also investigated to find that an efficient FRET process of the host-guest could occur at lower and neutral pH values (i.e., pH = 1–9) and in the normal temperature range of 25–40 °C. As the napthalimide can react with HS − anion to induce green turn-on emission behavior, the napthalimide-based mono-fluorophoric guest could detect HS − anion by turn-on photoluminescence with a corresponding limit of detection (LOD) value of 1.04 μM, which was also confirmed to possess a very high selectivity of HS − detection compared with another 23 analytes, including 16 anionic species. In contrast, the optimum LOD value of 0.30 μM for bi-fluorophoric host-guest polymer as a FRET-ON sensor material towards HS − detection was achieved due to the ratiometric emission of distinct color change from blue donor to green acceptor. Therefore, host-guest [2]pseudo-rotaxane polymer can be employed for the future bio-imaging applications of HS − anion detection in living cells. Graphical abstract: Image 1 Highlights: A FRET-ON [2]pseudo-rotaxane polymer contained blue-emissive anthracene guest and green-emissive napthalimide host. Towards HS − detection, [2]pseudo-rotaxane polymer showed the best FRET process in the THF/water solution (60% H2 O, v/v). Host-guest polymer towards HS − detection showed a better LOD value of 0.30 µM than that (1.04 μM) of napthalimide guest. Efficient FRET processes of bi-fluorophoric host-guest system could occur at pH=1-9 and a temperature range of 25-40 °C.