Antioxidant effects of continuous intake of electrolyzed hydrogen water in healthy adults. Issue 11 (November 2022)

• Record Type: Journal Article
• Authors: Mizuno, Kei; Watanabe, Kyosuke; Yamano, Emi; Ebisu, Kyoko; Tajima, Kanako; Nojima, Junzo; Ohsaki, Yusuke; Kabayama, Shigeru; Watanabe, Yasuyoshi
• Is Part Of: Heliyon. Volume 8:Issue 11(2022)
• Publication Date: 2022-11
• Subjects: Electrolyzed hydrogen water -- Antioxidant oxidative stress -- Inflammation -- LDL cholesterol -- Renal function; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2022.e11853
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: Chronic oxidative stress induces deterioration of health and a risk for the onset of various diseases. Previous clinical studies revealed that electrolyzed hydrogen water (EHW) is effective to reduce oxidative stress during hemodialysis in patients with chronic dialysis. In the present observational study, we investigated the antioxidant effects of a daily continuous intake of EHW in healthy adults. The concentrations of serum reactive oxygen metabolites-derived compounds (d-ROMs) and blood urea nitrogen in healthy volunteers (n = 64) who had a habit of intake over 500 mL/day of EHW at least 5 days a week for longer than 6 months were lower than those of age- and sex-matched controls (n = 470) without the habit of EHW intake. Oxidation stress index which the ratio between concentrations in d-ROMs and biological antioxidant potential was correlated with the serum concentration of high-sensitivity C-reactive protein or low-density lipoprotein cholesterol in the EHW group. These results suggest that the continuous intake of EHW induces antioxidant effects and may contribute to alleviate the risk of various oxidative stress-related dysfunctions and diseases in healthy adults. Abstract : Electrolyzed hydrogen water; Antioxidant oxidative stress; Inflammation; LDL cholesterol; Renal function.