Molecular diagnosis with the corresponding clinical symptoms of canine distemper virus infection in javan leopard (Panthera pardus ssp. melas). Issue 11 (November 2022)

• Record Type: Journal Article
• Authors: Rahman, Dede Aulia; Saepuloh, Uus; Santosa, Yanto; Darusman, Huda Shalahudin; Romaria Pinondang, Irene Margareth; Kindangen, Andy Sean; Pertiwi, Amira Putri; Sari, Lana; Irawan, Andi; Sultan, Keni; Rianti, Puji
• Is Part Of: Heliyon. Volume 8:Issue 11(2022)
• Publication Date: 2022-11
• Subjects: Canine distemper -- Conservation -- Diseases -- Leopard -- Environmental health; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2022.e11341
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: Diseases are one of the possible threats to the conservation of wild cat populations. One disease that has been reported to infect and cause death, including in various wildlife, is the canine distemper virus (CDV). Here, we report the first case of CDV in an adolescent melanistic Javan female leopard in Indonesia. We combined the clinical report with the Reverse Transcription PCR (RT-PCR) analyses on the faecal and brain samples of partial nucleoprotein ( CDV-N ) and hemagglutinin ( CDV-H ) genes. We also performed analyses of urine, haematology, and blood chemistry. The CDV-H nucleotide sequence confirmed the CDV infection in the female leopard and was clustered to the CDV's Asia 1 genotype. This finding opens an investigating window to analyse the pathogen transmission between animals in wildlife, particularly to support the management of conservation in natural habitats in Indonesia. Abstract : Canine distemper; Conservation; Diseases; Leopard; Environmental health.