CDKN2A exon 1B deletion predisposing to melanoma and neural system tumour syndrome. (25th October 2022)
- Record Type:
- Journal Article
- Title:
- CDKN2A exon 1B deletion predisposing to melanoma and neural system tumour syndrome. (25th October 2022)
- Main Title:
- CDKN2A exon 1B deletion predisposing to melanoma and neural system tumour syndrome
- Authors:
- Wong, Samantha L.
Martiniuc, Daniela
Kiuru, Maija - Abstract:
- Abstract : CDKN2A at chromosome positon 9p21 is a tumour suppressor gene encoding the cell cycle regulators p16 and p14ARF. While melanoma is associated with variants affecting both transcripts, families with mutations involving the p14ARF‐specific exon 1B may be predisposed to central nervous system tumours. We describe a family with a deletion of exon 1B in CDKN2A, who had multiple cutaneous melanomas, neural tumours and various malignancies.
- Is Part Of:
- Clinical and experimental dermatology. Volume 47:Number 12(2022)
- Journal:
- Clinical and experimental dermatology
- Issue:
- Volume 47:Number 12(2022)
- Issue Display:
- Volume 47, Issue 12 (2022)
- Year:
- 2022
- Volume:
- 47
- Issue:
- 12
- Issue Sort Value:
- 2022-0047-0012-0000
- Page Start:
- 2284
- Page End:
- 2285
- Publication Date:
- 2022-10-25
- Subjects:
- Skin -- Diseases -- Periodicals
616.5 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2230 ↗
https://academic.oup.com/ced/issue ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/ced.15354 ↗
- Languages:
- English
- ISSNs:
- 0307-6938
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3286.250000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 24431.xml