Impact of intracoronary assessments on revascularization decisions: A contemporary evaluation. Issue 6 (19th October 2022)

• Record Type: Journal Article
• Authors: Gillmore, Taylor; Jung, Richard G.; Moreland, Robert; Di Santo, Pietro; Stotts, Cameron; Makwana, Dwipen; Abdel‐Razek, Omar; Ahmed, Zeeshan; Chung, Kevin; Parlow, Simon; Simard, Trevor; Froeschl, Michael; Labinaz, Marino; Hibbert, Benjamin
• Is Part Of: Catheterization and cardiovascular interventions. Volume 100:Issue 6(2022)
• Page Start: 955
• Page End: 963
• Publication Date: 2022-10-19
• Subjects: clinical decision making -- fractional flow reserve -- intravascular ultrasound -- optical coherence tomography -- percutaneous coronary intervention; Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.30417
• Languages: English
• ISSNs: 1522-1946

Abstract

Abstract: Objectives: To investigate the real‐world implementation of intracoronary assessment (ICA) techniques and evaluate their impact on clinical decisions regarding the management of coronary artery disease (CAD) in contemporary practice. Background: Coronary angiogram is the gold standard used to diagnose vessel stenosis and guide percutaneous coronary intervention (PCI); however, it is limited by its two‐dimensional imaging capabilities. ICA techniques like intravascular ultrasound and optical coherence tomography capture the vessel in three‐dimensional images. Comparatively, fractional flow reserve provides information on the physiologic significance of coronary stenosis. Both techniques may improve PCI outcomes if they routinely change physician behavior. Methods: Patients who underwent ICA between August 2015 and March 2020 were included in the study. The primary outcome was the clinical impact of ICA on physician clinical decision making of a stenotic vessel. The secondary outcome was the clinical changes that occurred following ICA. Results: A total of 1135 patients were included in the study. Physiologic assessment (PA) and image assessment (IA) were performed in 61.4% and 38.6% respectively. Management plans were changed in 38.1% and 23.9% of patients who received PA and IA. Over half of the management change resulted in physicians deciding to not intervene on the stenotic vessel. One‐year outcome of these decisions showed no significant increase in major adverse cardiac events (hazard ratio [HR], 0.68; 95% confidence interval [CI], 0.40–1.15; p = 0.15) or unplanned revascularization (HR, 0.78; 95% CI, 0.35–1.74; p = 0.55) suggesting reliance on PA/IA data did not increase risk. Conclusion: Selected ICA alters physician management of CAD in one‐third of patients being evaluated for revascularization—typically leading to fewer interventions. All cause death is numerally lower in patients that received a change in management. However, the 1‐year outcome of these altered decisions does not appear to be significantly different.