Reactions and catalytic applications of a PNCNP pincer palladium hydride complex. Issue 46 (8th November 2022)

• Record Type: Journal Article
• Authors: Chang, Jiarui; Ding, Man; Mao, Jia-Xue; Zhang, Jie; Chen, Xuenian
• Is Part Of: Dalton transactions. Volume 51:Issue 46(2022)
• Page Start: 17602
• Page End: 17608
• Publication Date: 2022-11-08
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d2dt03131k
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : A PNCNP-pincer palladium hydride complex possesses strong deprotonating ability and versatile catalytic activity and its pincer backbone exhibits high water stability. Abstract : A palladium(ii ) hydride complex supported by a benzene-based PNCNP pincer ligand, [2, 6-( t Bu2 PNH)2 C6 H3 ]PdH (1 ), has been synthesized via two different routes: the reaction of the corresponding chloride complex with LiAlH4 and the reaction of the corresponding nitrate complex with KOCH3 . Complex 1 exhibits strong deprotonating ability and versatile catalytic activity. Acetamide can be readily deprotonated by complex 1 to form the corresponding acetamido complex, [2, 6-( t Bu2 PNH)2 C6 H3 ]PdNHC(O)CH3, in high yield. Complex 1 is an active catalyst for both the dehydrogenation of methanol to formaldehyde under mild conditions and direct hydration of nitriles to primary amides. Particularly, the direct hydration of nitriles to primary amides catalysed by complex 1 represents the most efficient palladium catalytic system for this type of reaction. A wide range of nitriles have been successfully hydrated to primary amides with 100% selectivity and good to excellent isolated yields. The possible reaction mechanisms are discussed.