Construction of diverse polycyclic N-heterocycles via cascade allylic amination/Diels–Alder reaction. Issue 95 (11th November 2022)

• Record Type: Journal Article
• Authors: Yang, Zhenkun; Xie, Hongling; Tang, Luning; Sun, Jianwei; Han, Zhengyu; Huang, Hai
• Is Part Of: Chemical communications. Volume 58:Issue 95(2022)
• Page Start: 13258
• Page End: 13261
• Publication Date: 2022-11-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc05208c
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An efficient cascade approach for the construction of nitrogen-containing polycyclic compounds from amines tethered with an alkenyl (or alkynyl) group and divinyl carbonates is described. Abstract : An efficient cascade approach for the construction of nitrogen-containing polycyclic compounds from amines tethered with an alkenyl (or alkynyl) group and divinyl carbonates is described. In the presence of Pd(0)-catalyst, an active zwitterionic allylpalladium species is generated and undergoes allylic amination with various amines followed by Diels–Alder reaction to form various polycyclic N -heterocyclic products, including hydrophenanthridines, hydrobenzo[ c ]azepines (hydro)isoindoles and hydrobenzo[ cd ]indoles.