Conventional MRI findings for predicting submandibular pleomorphic adenoma. (June 2013)

• Record Type: Journal Article
• Authors: Kashiwagi, Nobuo; Murakami, Takamichi; Nakanishi, Katsuyuki; Maenishi, Osamu; Okajima, Kaoru; Takahashi, Hiroto; Sakai, Mio; Tomita, Yasuhiko; Terao, Kyoichi; Tomiyama, Noriyuki
• Is Part Of: Acta radiologica. Volume 54:Number 5(2013)
• Page Start: 511
• Page End: 515
• Publication Date: 2013-06
• Subjects: Head/neck -- MR imaging -- salivary glands; Radiology, Medical -- Periodicals; Radiography, Medical -- Periodicals; Radiotherapy -- Periodicals; 616.0757
• DOI: 10.1177/0284185113475922
• Languages: English
• ISSNs: 0284-1851

Abstract

Background: Although pleomorphic adenomas account for over 90% of all benign submandibular gland tumors, the imaging features of submandibular pleomorphic adenomas have not been reported in a large number of cases. Purpose: To assess the conventional magnetic resonance imaging (MRI) findings for predicting the submandibular pleomorphic adenoma. Material and Methods: MR studies of 42 pleomorphic adenomas and 28 other types of tumor were reviewed. MR images were assessed for the presence of hyperintense areas on T2-weighted images (first sign), a well-defined margin (second sign), and presence of crescent-shaped compression of the ipsilateral normal submandibular gland (third sign). Results: For identifying submandibular pleomorphic adenoma, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 97.6%, 50.0%, 74.5%, 93.3%, and 78.6% for the first sign, 95.2%, 46.4% 72.7%, 86.7%, and 75.7% for the second sign, and 23.8%, 100%, 86.7%, 46.7%, and 54.3% for the third sign, respectively. Combining the first and second findings achieved to 85.7% specificity and 90.9% accuracy. Conclusion: Although non-specific, submandibular pleomorphic adenomas usually have hyperintense areas on T2-weighted images and well-defined margins. In addition, crescent-shaped compression of the ipsilateral normal gland seems to represent a highly specific sign.