Making a head: Neural crest and ectodermal placodes in cranial sensory development. (30th March 2023)

• Record Type: Journal Article
• Authors: Koontz, Alison; Urrutia, Hugo A.; Bronner, Marianne E.
• Is Part Of: Seminars in cell & developmental biology. Volume 138(2023)
• Page Start: 15
• Page End: 27
• Publication Date: 2023-03-30
• Subjects: Ectodermal placode -- Neural crest -- Sensory system -- Vertebrate evolution; Cytology -- Periodicals; Developmental biology -- Periodicals; 571.6
• DOI: 10.1016/j.semcdb.2022.06.009
• Languages: English
• ISSNs: 1084-9521

Abstract

Abstract: During development of the vertebrate sensory system, many important components like the sense organs and cranial sensory ganglia arise within the head and neck. Two progenitor populations, the neural crest, and cranial ectodermal placodes, contribute to these developing vertebrate peripheral sensory structures. The interactions and contributions of these cell populations to the development of the lens, olfactory, otic, pituitary gland, and cranial ganglia are vital for appropriate peripheral nervous system development. Here, we review the origins of both neural crest and placode cells at the neural plate border of the early vertebrate embryo and investigate the molecular and environmental signals that influence specification of different sensory regions. Finally, we discuss the underlying molecular pathways contributing to the complex vertebrate sensory system from an evolutionary perspective, from basal vertebrates to amniotes.