Hospitalization for COVID-19 is associated with a higher risk of subsequent hospitalization for psychiatric disorders: A French nationwide longitudinal study comparing hospitalizations for COVID-19 and for other reasons. Issue 1 (21st October 2022)

• Record Type: Journal Article
• Authors: Decio, Valentina; Pirard, Philippe; Pignon, Baptiste; Bouaziz, Olivier; Perduca, Vittorio; Chin, Francis; Le Strat, Yann; Messika, Jonathan; Kovess-Masfety, Viviane; Corruble, Emmanuelle; Regnault, Nolwenn; Tebeka, Sarah
• Is Part Of: European psychiatry. Volume 65:Issue 1(2022)
• Publication Date: 2022-10-21
• Subjects: COVID-19 -- epidemiology -- hospitalization -- psychiatric disorders -- SNDS; Psychiatry -- Periodicals; Mental illness -- Periodicals; Electronic journals; 616.89
• DOI: 10.1192/j.eurpsy.2022.2331
• Languages: English
• ISSNs: 0924-9338

Abstract

Abstract: Introduction: Although COVID-19 has been associated with psychiatric symptoms in patients, no study to date has examined the risk of hospitalization for psychiatric disorders after hospitalization for this disease. Objective: We aimed to compare the proportions of hospitalizations for psychiatric disorders in the 12 months following either hospitalization for COVID-19 or hospitalization for another reason in the adult general population in France during the first wave of the current pandemic. Methods: We conducted a retrospective longitudinal nationwide study based on the national French administrative healthcare database. Results: Among the 2, 894, 088 adults hospitalized, 96, 313 (3.32%) were admitted for COVID-19. The proportion of patients subsequently hospitalized for a psychiatric disorder was higher for COVID-19 patients (11.09 vs. 9.24%, OR = 1.20 95%CI 1.18–1.23). Multivariable analyses provided similar results for a psychiatric disorder of any type and for psychotic and anxiety disorders (respectively, aOR = 1.06 95%CI 1.04–1.09, aOR = 1.09 95%CI 1.02–1.17, and aOR = 1.11 95%CI 1.08–1.14). Initial hospitalization for COVID-19 in intensive care units and psychiatric history were associated with a greater risk of subsequent hospitalization for any psychiatric disorder than initial hospitalization for another reason. Discussion: Compared with hospitalizations for other reasons, hospitalizations for COVID-19 during the first wave of the pandemic in France were associated with a higher risk of hospitalization for a psychiatric disorder during the 12 months following initial discharge. This finding should encourage clinicians to increase the monitoring and assessment of psychiatric symptoms after hospital discharge for COVID-19, and to propose post-hospital care, especially for those treated in intensive care.