Role of extracellular vesicles in intercellular communication during reproduction. (24th July 2022)

• Record Type: Journal Article
• Authors: Godakumara, Kasun; Dissanayake, Keerthie; Hasan, Mohammad Mehedi; Kodithuwakku, Suranga. P.; Fazeli, Alireza
• Is Part Of: Reproduction in domestic animals. Volume 57(2022)Supplement 5
• Page Start: 14
• Page End: 21
• Publication Date: 2022-07-24
• Subjects: embryo‐maternal communication -- extracellular vesicles -- immune regulation -- intercellular signalling -- maternal recognition of pregnancy; Animal breeding -- Periodicals; Veterinary pathology -- Periodicals; Livestock -- Breeding -- Periodicals; 636.082
• DOI: 10.1111/rda.14205
• Languages: English
• ISSNs: 0936-6768

Abstract

Abstract: The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo and the maternal system. Extracellular vesicles (EVs) are involved in these communications to a significant degree from the gamete production and maturation to fertilization, embryo development and implantation. They regulate the cellular physiology and the immune reaction to bring about a favourable environment for a successful pregnancy. Deciphering the mechanisms employed in EV‐mediated embryo maternal communication could improve our knowledge in mammalian reproduction and increase the efficiency of animal breeding.