Thalamocortical and corticothalamic connections of multiple functional domains in posterior parietal cortex of galagos. Issue 1 (18th September 2022)

• Record Type: Journal Article
• Authors: Wang, Qimeng; Stepniewska, Iwona; Liao, Chia‐Chi; Kaas, Jon H.
• Is Part Of: Journal of comparative neurology. Volume 531:Issue 1(2023)
• Page Start: 25
• Page End: 47
• Publication Date: 2022-09-18
• Subjects: anatomical tracing -- long‐train stimulation -- motor thalamus -- primate -- pulvinar; Comparative neurobiology -- Periodicals; Neurology -- Periodicals; 616
• DOI: 10.1002/cne.25410
• Languages: English
• ISSNs: 0021-9967

Abstract

Abstract: In prosimian galagos, the posterior parietal cortex (PPC) is subdivided into a number of functional domains where long‐train intracortical microstimulation evoked different types of complex movements. Here, we placed anatomical tracers in multiple locations of PPC to reveal the origins and targets of thalamic connections of four PPC domains for different types of hindlimb, forelimb, or face movements. Thalamic connections of all four domains included nuclei of the motor thalamus, ventral anterior and ventral lateral nuclei, as well as parts of the sensory thalamus, the anterior pulvinar, posterior and ventral posterior superior nuclei, consistent with the sensorimotor functions of PPC domains. PPC domains also projected to the thalamic reticular nucleus in a somatotopic pattern. Quantitative differences in the distributions of labeled neurons in thalamic nuclei suggested that connectional patterns of these domains differed from each other. Abstract : The posterior parietal cortex (PPC) of galagos contains a series of domains where electrical stimulation evokes different types of complex movements. The medial domains have more connections with the motor thalamus, whereas the lateral domains connect more densely with the posterior thalamus that involves in somatosensory processing.