142 Middle Ear Adenoma: A Rare Case. (11th January 2018)

• Record Type: Journal Article
• Authors: AlZubaidi, Yasir; Abdulsattar, Jehan; Al, Firas; Herrera, Guillermo
• Is Part Of: American journal of clinical pathology. Volume 149(2018)Supplement 1
• Page Start: S61
• Page End: S61
• Publication Date: 2018-01-11
• Subjects: Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; 616.07
• DOI: 10.1093/ajcp/aqx119.141
• Languages: English
• ISSNs: 0002-9173

Abstract

Abstract: Middle ear adenoma (MEA) is an uncommon (<2% of ear tumors) benign glandular neoplasm of the middle ear. MEA occurs equally in both genders and over a wide age range, but it is most common in the third to fifth decade of life. Any portion of the middle ear may be affected, including the Eustachian tube, mastoid air spaces, ossicles, and chorda tympani nerve. The most common symptom is unilateral conductive hearing loss, but fullness, tinnitus, and dizziness may also occur. In the majority of cases, otoscopic examination identifies an intact tympanic membrane with a tumor that is confined to the middle ear space with possible extension to the mastoid. Here we report a case of a 15-year-old boy with a two-year history of hearing loss and fullness of the left ear. Physical examination of the tympanic membrane reveals posterior superior retraction with some debris that was difficult to remove. Excision of the lesion was performed. Microscopic examination revealed a dual cell population: inner luminal cells with eosinophilic cytoplasm and outer cuboidal/columnar cells with indistinct cytoplasm. The nuclei are round to oval, eccentrically placed "plasmacytoid, " with minimal pleomorphism and dispersed chromatin pattern. No mitotic figures were noted. Immunohistochemical stains showed strong AE1/AE3, CAM5.2. Based on the morphology and immunohistochemistry, a diagnosis of middle ear adenoma was rendered.