Orthotopic Heart Transplant for Treatment-Resistant Cardiomyopathy in Kawasaki Syndrome: Report of a Successful Case. (December 2013)

• Record Type: Journal Article
• Authors: Mirhosseini, Seyed Mohsen; Asadollahi, Shadi; Fakhri, Mohammad
• Is Part Of: Progress in transplantation. Volume 23:Number 4(2013)
• Page Start: 371
• Page End: 373
• Publication Date: 2013-12
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation; Organ Procurement; Tissue Donors; Transplantation of organs, tissues, etc; Electronic journals; Periodicals; Periodicals; 362.1783
• DOI: 10.7182/pit2013252
• Languages: English
• ISSNs: 1526-9248

Abstract

Kawasaki disease is a systemic vascular inflammatory disorder of yet unknown cause that is associated with critical cardiovascular complications. Several long-term medical therapies, coronary revascularization, and heart transplant have been introduced to treat coronary artery lesions. This report describes a 20-year-old man with Kawasaki disease manifesting as intermittent chest pain and nausea who had advanced decompensated cardiomyopathy (ejection fraction, 15%) diagnosed. Coronary artery bypass surgery and implantation of a cardioverter defibrillator had been performed, although no significant clinical improvement was observed. Finally, a successful orthotopic bicaval heart transplant was performed. Follow-up examination after 1 year revealed normal cardiac function with no evidence of organ rejection. This experience demonstrated that heart transplant might be a successful method of treating permanent ischemic cardiomyopathy in patients with Kawasaki syndrome.