2, 2'-Dipyridylamine: A tripod ligand enabling practical access to diaryl ethers via Cu-catalyzed coupling reaction. Issue 22 (17th November 2022)

• Record Type: Journal Article
• Authors: Chen, Yuanguang; Xu, Huashen; Chen, Lu; Hou, Anyuan; Chen, Guoliang
• Is Part Of: Synthetic communications. Volume 52:Issue 22(2022)
• Page Start: 2163
• Page End: 2170
• Publication Date: 2022-11-17
• Subjects: Diaryl ethers -- copper catalyst -- 2, 2'-dipyridylamine -- tripod ligand -- diaryl thioethers; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2022.2134797
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: 2, 2'-dipyridylamine (DPA) is hereby firstly reported as a novel and efficient tridentate ligand for promoting copper(I)-catalyzed C-O/S coupling reactions of abundant aryl bromines with related phenols or thiophenols. The key to this very discovery is the identification of an N -donor tripod ligand (DPA), and such a reaction allows the conversion of simple starting materials to complex diaryl ethers or diaryl thioethers, which are important synthetic intermediates in the preparation of bioactive molecules. Graphical Abstract: UF0001