A metal–organic framework loaded paper-based chemiluminescence sensor for trace acetone detection in exhaled breath. Issue 44 (3rd November 2022)

• Record Type: Journal Article
• Authors: Lv, Congcong; Hou, Yue; Guo, Yanli; Ma, Xiaohu; Zhang, Yu; Liu, Yuchuan; Jin, Yan; Li, Baoxin; Liu, Wei
• Is Part Of: Analytical methods. Volume 14:Issue 44(2022)
• Page Start: 4514
• Page End: 4522
• Publication Date: 2022-11-03
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/d2ay01025a
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : A paper-based CL gas sensor was established for sensitive detection of trace acetone in exhaled breath. UiO-66 with an adsorption function was in situ synthesized on the paper-based device. Abstract : Trace acetone determination in breath can be regarded as a noninvasive method for diagnosis of diabetes. Here, a paper-based CL gas sensor combined with UiO-66 as the preconcentrator was established for sensitive detection of trace acetone in exhaled breath. UiO-66 with excellent adsorption performance and unique water stability was used for the adsorption and enrichment of acetone gas under high humidity conditions in exhaled breath. As acetone can remarkably increase the chemiluminescence (CL) of the 2, 4-dinitrophenylhydrazine (DNPH)–potassium permanganate (KMnO4 ) system, a sensitive CL device based on a paper substrate for trace acetone detection was established and the detection limit was 0.03 ppm. The fabricated method was used to assess the content of trace acetone in exhaled breath with satisfactory recoveries of 90–110%. It is expected to realize the noninvasive determination of acetone for diabetic patients in exhaled breath.