Effectiveness estimates for enhanced trivalent influenza vaccines in an aged care summer outbreak. Issue 50 (28th November 2022)

• Record Type: Journal Article
• Authors: Kunasekaran, Mohana; Moa, Aye; Hooshmand, Elmira; Trent, Mallory; Poulos, Christopher J.; Chughtai, Abrar A.; Heslop, David J.; Raina MacIntyre, C.
• Is Part Of: Vaccine. Volume 40:Issue 50(2022)
• Page Start: 7170
• Page End: 7175
• Publication Date: 2022-11-28
• Subjects: Aged care -- Adjuvanted trivalent vaccines -- High-dose trivalent vaccine -- Influenza -- Outbreak; Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2022.06.018
• Languages: English
• ISSNs: 0264-410X

Abstract

Abstract: An influenza outbreak occurred during summer (February 2019) in an aged-care facility in Sydney, Australia. Residents had not received the annual 2019 influenza vaccine while 76.7% had received 2018 influenza vaccines about 9 months prior. Overall, 2018 influenza vaccine effectiveness during this outbreak was high (93.6%). The effectiveness of the high-dose trivalent vaccine (HD-TIV) and adjuvanted trivalent (a-TIV) vaccine were 89.8% (95% confidence interval: 18.8%-98.7%) and 72.5% (95% confidence interval: −106.7%-96.3%) respectively. The differences in effectiveness between HD-TIV, a-TIV and SD-QIV, during the summer outbreak were not significant.