A "light" touch on PI3K to interrogate cancer drug resistance. Issue 11 (17th November 2022)
- Record Type:
- Journal Article
- Title:
- A "light" touch on PI3K to interrogate cancer drug resistance. Issue 11 (17th November 2022)
- Main Title:
- A "light" touch on PI3K to interrogate cancer drug resistance
- Authors:
- Wang, Tianlu
Ke, Yuepeng
Zhou, Yubin - Abstract:
- Abstract : In this issue of Cell Chemical Biology, Ueda et al. (2022) developed PPAP2 as an improved optogenetic tool to photo-induce PI3K signaling hyperactivation in cancer cells. They demonstrated that enhanced translation of tumor necrosis factor alpha-induced protein 8 (TNFAIP8) might explain PI3K hyperactivation-associated resistance toward DNA damaging anti-cancer alkylating agents. Abstract : In this issue of Cell Chemical Biology, Ueda et al. (2022) developed PPAP2 as an improved optogenetic tool to photo-induce PI3K signaling hyperactivation in cancer cells. They demonstrated that enhanced translation of tumor necrosis factor alpha-induced protein 8 (TNFAIP8) might explain PI3K hyperactivation-associated resistance toward DNA damaging anti-cancer alkylating agents.
- Is Part Of:
- Cell chemical biology. Volume 29:Issue 11(2022)
- Journal:
- Cell chemical biology
- Issue:
- Volume 29:Issue 11(2022)
- Issue Display:
- Volume 29, Issue 11 (2022)
- Year:
- 2022
- Volume:
- 29
- Issue:
- 11
- Issue Sort Value:
- 2022-0029-0011-0000
- Page Start:
- 1573
- Page End:
- 1575
- Publication Date:
- 2022-11-17
- Subjects:
- Biochemistry -- Periodicals
572.05 - Journal URLs:
- http://www.cell.com/cell-chemical-biology/home ↗
http://www.sciencedirect.com/ ↗ - DOI:
- 10.1016/j.chembiol.2022.11.005 ↗
- Languages:
- English
- ISSNs:
- 2451-9456
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3097.733000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 24315.xml