Current practices in pediatric hospital‐acquired thromboembolism: Survey of the Children's Hospital Acquired Thrombosis (CHAT) Consortium. Issue 7 (5th October 2022)

• Record Type: Journal Article
• Authors: Abrams, Christina M.; Jaffray, Julie; Stillings, Amy; Branchford, Brian R.; Young, Guy; Goldenberg, Neil A.; Abajas, Yasmina L.
• Other Names: Fargo John investigator.; Crary Shelly investigator.; Kumar Riten investigator.; Woods Gary investigator.; Narang Shalu investigator.; Cooper James investigator.; Silvey Mike investigator.; Garland Kate investigator.; Mahajerin Arash investigator.; Luchtman‐Jones Lori investigator.; Torres Marcela investigator.; Wright Jordan investigator.; Pahl Kristy investigator.; Armstrong Katherine investigator.; Braunreiter Chi investigator.; Bakeer Nihal investigator.; Sochet Anthony investigator.; Hogan Marie investigator.; Gupta Shveta investigator.; Knoll Christine investigator.; Hege Kerry investigator.; Schaefer Beverly investigator.; Panigrahi Arun investigator.; Thornburg Courtney investigator.; Shimano Kristin investigator.; Ahuja Sanjay investigator.; Weyand Angela investigator.; Boucher Alexander investigator.; Abajas Yasmina investigator.; Subbaswamy Anjali investigator.; Khan Osman investigator.; Druzgal Colleen investigator.; Maida Deanna investigator.; Wheeler Allison investigator.; Malec Lynn investigator.; Branchford Brian investigator.; Kucine Nicole Elena investigator.; Prozora Stephanie investigator.;
• Is Part Of: Research and practice in thrombosis and haemostasis. Volume 6:Issue 7(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-05
• Subjects: anticoagulants -- hospital -- pediatric -- risk assessment -- risk factors -- venous thromboembolism; Thrombosis -- Periodicals; Hemostasis -- Periodicals; 616.135005
• DOI: 10.1002/rth2.12793
• Languages: English
• ISSNs: 2475-0379

Abstract

Abstract: Background: A rise in hospital‐acquired venous thromboembolism (HA‐VTE) in children has led to increased awareness regarding VTE prophylaxis and risk assessment. Despite this, no consensus exists regarding these practices in pediatrics. Objective: To describe common practices in VTE prophylaxis, VTE risk assessment models, and anticoagulation dosing strategies in pediatric hospitals that are members of the Children's Hospital Acquired Thrombosis (CHAT) Consortium. Methods: An electronic survey of 44 questions evaluating practices surrounding pediatric HA‐VTE risk assessment and prevention was distributed between August 9, 2021, and August 30, 2021, to the primary investigators from the 32 institutions within the CHAT Consortium. Results: The survey response rate was 100% ( n = 32). In total, 85% ( n = 27) of the institutions assess HA‐VTE, but only 63% ( n = 20) have formal hospital guidelines. Within the institutions with formal guidelines, 100% ( n = 20) include acute systemic inflammation or infection and presence of a central venous catheter (CVC) as risk factors for VTE. Pharmacologic prophylaxis is prescribed at 87% (28) of institutions, with enoxaparin being the most frequent (96%, n = 27). Variability in responses persisted regarding risk factors, risk assessment, thromboprophylaxis, dosing of prophylactic anticoagulation or anticoagulant drug monitoring. A majority of providers were comfortable providing thromboprophylaxis across all age groups. In addition, the global coronavirus disease 2019 increased the providers' use of prophylactic anticoagulation 78% ( n = 25). Conclusion: Practices among institutions are variable in regard to use of HA‐VTE prophylaxis, risk assessment, or guideline implementation, highlighting the need for further research and a validated risk assessment model through groups like the CHAT Consortium.