SIRT6: therapeutic target for nonalcoholic fatty liver disease. (December 2022)
- Record Type:
- Journal Article
- Title:
- SIRT6: therapeutic target for nonalcoholic fatty liver disease. (December 2022)
- Main Title:
- SIRT6: therapeutic target for nonalcoholic fatty liver disease
- Authors:
- Zang, Mengwei
Gao, Bin - Abstract:
- Abstract: Recently, Hou et al . shifted the research focus from the function of nuclear sirtuin (SIRT)6 to that of cytoplasmic SIRT6, which deacetylates and activates long-chain acyl-CoA synthase 5 (ACSL5). Their findings provide mechanistic insight into the role of cytoplasmic SIRT6 in fatty acid oxidation, acting as a therapeutic target for combating nonalcoholic fatty liver disease (NAFLD).
- Is Part Of:
- Trends in endocrinology and metabolism. Volume 33:Number 12(2022)
- Journal:
- Trends in endocrinology and metabolism
- Issue:
- Volume 33:Number 12(2022)
- Issue Display:
- Volume 33, Issue 12 (2022)
- Year:
- 2022
- Volume:
- 33
- Issue:
- 12
- Issue Sort Value:
- 2022-0033-0012-0000
- Page Start:
- 801
- Page End:
- 803
- Publication Date:
- 2022-12
- Subjects:
- SIRT6 -- deacetylation -- long-chain acyl-CoA synthase 5 -- fatty acid oxidation -- lipid metabolism -- nonalcoholic fatty liver disease
Endocrinology -- Periodicals
Metabolism -- Periodicals
Metabolism
616.4 - Journal URLs:
- http://www.elsevier.com/journals ↗
http://www.sciencedirect.com/science/journal/10432760 ↗ - DOI:
- 10.1016/j.tem.2022.10.004 ↗
- Languages:
- English
- ISSNs:
- 1043-2760
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.590500
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 24342.xml