Squarate-Based Metal-Organic Frameworks for Highly Selective and Sensitive Electrochemical Sensing of Dopamine. Issue 11 (1st November 2022)

• Record Type: Journal Article
• Authors: Zhang, Wen; Zheng, Xinyue; Jia, Gan; Chi, Hongzhong; Lin, Bao; Qin, Haiying; Xie, Haijiao; Yuan, Yongjun; Fu, Degang
• Is Part Of: Journal of the Electrochemical Society. Volume 169:Issue 11(2022)
• Publication Date: 2022-11-01
• Subjects: Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/1945-7111/ac9f7c
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : Dopamine (DA) is an important catecholamine neurotransmitter associated with learning, depression, addiction, and memory loss with simultaneously coordinating movement and reward-associated behavior. It is very important to design highly effective and sensitive sensors for the detection of DA. However, it remains a challenge for detecting DA to obtain selectively and rapidly sensing materials. In this work, we chose octahedral-coordinated squarate-based MOFs with dense Lewis active centers as electrode materials to investigate the electrochemical performance of dopamine oxidation. The multiple ligand functional groups in squarate-based MOFs enable noncovalent interaction with diols, amines, and phenyl groups of DA molecules through electrostatic, H-bonding, and/or π – π stacking interactions. The modified electrode exhibits a wide linear current response range between 2 μ M and 400 μ M for DA, and the sensor shows significant selectivity and stability. This work enriches the application library of redox-active squarate compounds and can give us a better comprehension of the design and selection of electrode materials for electrochemical sensing and even more catalysis-related research.