Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids. (1st December 2019)

• Record Type: Journal Article
• Authors: Ghaffari, Roozbeh; Choi, Jungil; Raj, Milan S.; Chen, Shulin; Lee, Stephen P.; Reeder, Jonathan T.; Aranyosi, Alexander J.; Leech, Adam; Li, Weihua; Schon, Stephanie; Model, Jeffrey B.; Rogers, John A.
• Is Part Of: Advanced functional materials. Volume 30:Number 37(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-12-01
• Subjects: bioassays -- bioelectronics -- electrochemistry -- microfluidics -- personalized medicine; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201907269
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract: Wearable monitoring systems provide valuable insights about the state of wellness, performance, and progression of diseases. Although conventional wearable systems have been effective in measuring a few key biophysical markers, they offer limited insights into biochemical activity and are otherwise cumbersome in ambulatory modes of use, relying on wired connections, mechanical straps, and bulky electronics. Recent advances in skin‐interfaced microfluidics, stretchable/flexible electronics, and mechanics have created new wearable systems with capabilities in real‐time, noninvasive analysis of sweat biochemistry in combination with biophysical metrics. Here, the latest technologies in multifunctional sweat sensing systems are presented with a focus on novel microfluidic designs, fully‐integrated wireless electrochemical sensors, and hybrid biochemical/biophysical sensing capabilities, creating real‐time physiological insights. Abstract : Wearable health monitoring systems provide important insights into the state of wellness, performance, and progression of diseases, but are otherwise cumbersome in ambulatory modes of use. Here, the latest wearable biochemical sensing technologies are reviewed with a focus on microfluidic designs, electrochemical sensors, and hybrid biochemical/biophysical systems.