Self‐Assemblies of DNA ‐ Amphiphiles Nanostructures for New Design Strategies of Varied Morphologies. Issue 38 (10th October 2022)

• Record Type: Journal Article
• Authors: Mathew, Shilpa Sarah; Ahamed, A A Subuhan; Abraham, Ignatious; Prabhu, Deepak D; John, Franklin; George, Jinu
• Is Part Of: ChemistrySelect. Volume 7:Issue 38(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-10
• Subjects: DNA Amphiphiles -- Self-assembly -- Nanostructures -- Drug Delivery; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202202146
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: This review throws light upon the functionalization of DNA amphiphiles which upon self‐assembly give rise to nanostructures of varied morphology and novelty. Such nanostructures comprising of micelles, vesicles, sheets or ribbons find a multitude of applications in medical field, specially in drug delivery. Emphasis has been laid upon the self‐assembly process of DNA based amphiphiles which prove excellent drug carriers by making use of the unique structural features of DNA. Further insights may also aid in developing modified nanostructures based on DNA out of subsequent derivatization. Abstract : This Review depicts in detail the types of DNA nano structures used for efficient drug delivery. Different Morphologies of nano structures formed from the self joining mechanism of DNA based species are highlighted and new frontiers in this field were explored scrupulously.