Outcomes of surgical versus non-surgical treatment of resectable T4a laryngeal and hypopharyngeal carcinoma. Issue 11 (18th November 2022)

• Record Type: Journal Article
• Authors: Thiagarajan, S; Gupta, M; Sathe, P; Gill, G; Ghosh-Laskar, S; Prabhash, K; Chaukar, D
• Is Part Of: Journal of laryngology & otology. Volume 136:Issue 11(2022)
• Page Start: 1087
• Page End: 1095
• Publication Date: 2022-11-18
• Subjects: Carcinoma Larynx -- Carcinoma Hypopharynx -- T4a -- Treatment Pattern; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1017/S0022215121004461
• Languages: English
• ISSNs: 0022-2151

Abstract

Abstract: Objective: Surgery is the recommended treatment for resectable T4 a laryngeal and hypopharyngeal carcinoma. Non-surgical treatment is an option in a select few patients. Method: This retrospective study was undertaken to assess the treatment outcomes in patients with resectable T4 a carcinoma of the larynx and hypopharynx who received either surgical or non-surgical treatment at our institute and to assess factors influencing these outcomes. Results: A total of 120 patients were included in the study. They were divided into groups A, B and C based on the presence of extralaryngeal spread through laryngeal membrane, cartilage or both. The overall survival was better among patients who received surgery than those who received non-surgical treatment in the three groups. The factor influencing overall survival was the treatment given in the form of surgical versus non-surgical treatment. Conclusion: Surgery is the preferred treatment for T4 a laryngeal and hypopharyngeal carcinoma, even in patients with extralaryngeal spread without cartilage erosion.