Melatonin mediated activation of MAP kinase pathway may reduce DNA damage stress in plants: A review. (8th August 2022)

• Record Type: Journal Article
• Authors: Maity, Sukhendu; Guchhait, Rajkumar; Pramanick, Kousik
• Is Part Of: BioFactors. Volume 48:Number 5(2022)
• Page Start: 965
• Page End: 971
• Publication Date: 2022-08-08
• Subjects: abiotic stress -- antioxidant -- cyclin‐CDK -- DNA damage -- MAP kinase -- melatonin -- MYBs -- SOG1; Vitamins -- Physiological effect -- Periodicals; Trace elements -- Physiological effect -- Periodicals; Growth factors -- Physiological effect -- Periodicals; Plant growth promoting substances -- Physiological effect -- Periodicals; Biochemistry -- Periodicals; Nutritional Physiological Phenomena -- Periodicals; Trace Elements -- metabolism -- Periodicals; Vitamins -- metabolism -- Periodicals; Molecular Biology -- Periodicals; 612.399
• DOI: 10.1002/biof.1882
• Languages: English
• ISSNs: 0951-6433

Abstract

Abstract: Melatonin is an important biomolecule found in diverse groups of organisms. Under different abiotic stresses, the synthesis of melatonin is markedly increased suggesting pivotal roles of melatonin in plants enduring stresses. Being an endogenous signaling molecule with antioxidant activity, melatonin alters many physiological responses and is found to be involved in regulating DNA damage responses. However, the molecular mechanisms of melatonin in response to DNA damage have not yet been studied. The present review aims to provide insights into the molecular mechanisms of melatonin in response to DNA damage in plants. We propose that the MAP kinase pathway is involved in regulating melatonin dependent response of plants under DNA damage stress. Where melatonin might activate MAPK via H2 O2 or Ca 2+ dependent pathways. The activated MAPK in turn might phosphorylate and activate SOG1 and repressor type MYBs to mitigate DNA damage under abiotic stress.