Split-face comparison of the efficacy of picosecond 532 nm Nd:YAG laser and Q-switched 755 nm Alexandrite laser for treatment of freckles. (4th July 2022)

• Record Type: Journal Article
• Authors: Ma, Shao-Yin; Gong, Ye-Qing; Zhang, Wen- Jun; Liang, Bi-Hua; Li, Yue-Ming; Xie, Zhi-Min; Zhu, Hui-Lan
• Is Part Of: Journal of cosmetic and laser therapy. Volume 24:Number 1-5(2022)
• Page Start: 22
• Page End: 27
• Publication Date: 2022-07-04
• Subjects: Freckles -- picosecond laser -- alexandrite laser; Skin -- Laser surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.477
• DOI: 10.1080/14764172.2022.2049311
• Languages: English
• ISSNs: 1476-4172

Abstract

ABSTRACT: To date, there has been little study of comparison between picosecond 532 nm laser and 755 nm Q-switched Alexandrite lasers in the treatment of freckles. To evaluate the efficacy and safety of picosecond 532 nm laser (PS 532) and 755 nm Q-switched Alexandrite laser (QSAL) for treatment of freckles in a split-face manner. Eighteen patients with freckles were enrolled in the study. The right and left sides of their faces were randomly assigned to either a QSAL-treated group or PS 532-treated group. The degree of pain, satisfaction with the results, and adverse events associated with the laser treatment were evaluated using a questionnaire. All of the patients were followed up at 4 and 12 weeks after one treatment session. Among the 18 patients, PS 532 was found to be associated with less pain (3.56 ± 2.431) than QSAL (3.94 ± 1.893), but the difference was not statistically significant. The curative effect and satisfaction associated with 755 nm Q-switched Alexandrite laser was greater than that of picosecond 532 nm laser (P < .001). Both picosecond 532 nm laser and QSAL are effective in the treatment of freckles, and QSAL has a greater rate of satisfaction and curative effect.