Exploring the boundaries of ferrocenesulfonyl fluoride chemistry. Issue 22 (4th October 2022) - Erb, William
Abstract : The first general study dedicated to hetero polysubstituted ferrocenesulfonyl fluorides is described. Their chemical behaviour in various reaction conditions is reported as well as their electrochemical properties. Abstract : Ferrocenesulfonyl fluorides represent a new subfamily of metallocenes barely explored. Here, we describe how the use of deprotolithiation-electrophilic trapping sequences and 'halogen dance' reactions can afford up to 1, 2, 3, 4, 5-hetero pentasubstituted derivatives. While the orthogonal reactivity of ferrocenesulfonyl fluorides was demonstrated in a variety of transformations, SuFEx chemistry afforded various sulfur-based ferrocene derivatives. The electrochemical behaviour of many polysubstituted derivatives was studied and discussed as well as weak interactions identified in the solid state.