Genomic reorganization by IS26in ablaNDM‐5‐bearing FII plasmid ofKlebsiella pneumoniaeisolated from a patient in Japan. Issue 9 (September 2018)

• Record Type: Journal Article
• Authors: Takeuchi, Dan; Akeda, Yukihiro; Yoshida, Hisao; Hagiya, Hideharu; Yamamoto, Norihisa; Nishi, Isao; Yoshioka, Nori; Sugawara, Yo; Sakamoto, Noriko; Shanmugakani, Rathina Kumar; Deguchi, Matsuo; Tomono, Kazunori; Hamada, Shigeyuki
• Is Part Of: Journal of medical microbiology. Volume 67:Issue 9(2018)
• Publication Date: 2018-09
• Subjects: blaNDM‐5 -- IS26 -- IncFII plasmid -- genomic reorganization; Medical microbiology -- Periodicals; 616.9041
• DOI: 10.1099/jmm.0.000817
• Languages: English
• ISSNs: 0022-2615

Abstract

Abstract : N/A: An NDM‐5‐producing Klebsiella pneumoniae ST147 strain was isolated from a Japanese patient who had not travelled abroad in at least 5 years. Whole‐genome sequencing revealed a genomic rearrangement in an FII plasmid harbouring bla NDM‐5 due to the replicative transposition of IS 26 . A hypothetical structure was proposed for its ancestral plasmid, and comparative genomic analysis of the plasmid suggested the dissemination of structurally similar plasmids harbouring bla NDM‐5 in Asian and Middle Eastern countries.