Ultraselective Carbon Nanotubes for Photoacoustic Imaging of Inflamed Atherosclerotic Plaques (Adv. Funct. Mater. 37/2021). (9th September 2021)

• Record Type: Journal Article
• Authors: Gifani, Mahsa; Eddins, Devon J.; Kosuge, Hisanori; Zhang, Yapei; Paluri, Sesha L. A.; Larson, Timothy; Leeper, Nicholas; Herzenberg, Leonore A.; Gambhir, Sanjiv Sam; McConnell, Michael V.; Ghosn, Eliver E. B.; Smith, Bryan Ronain
• Is Part Of: Advanced functional materials. Volume 31:Number 37(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-09-09
• Subjects: atherosclerosis -- carbon nanotubes -- diagnostic imaging -- flow cytometry -- immunoimaging -- photoacoustic imaging; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.202170271
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : Ultraselective Carbon Nanotubes Vulnerable atherosclerotic plaques can result in heart attacks. Inflammation, particularly inflammatory monocytes/macrophages, characterizes such plaques. In article number 2101005, Eliver E. B. Ghosn, Bryan Ronain Smith, and co‐workers present single‐walled carbon nanotubes' unprecedented selectivity to inflammatory monocytes/macrophages that infiltrate plaques, allowing specific detection of inflamed plaques using photoacoustic imaging (laser in, ultrasound out). This highly selective strategy, confirmed by high‐dimensional flow cytometry, can accurately identify and diagnose inflamed atherosclerotic lesions.