A Rare Case of Metastatic Hepatocellular Carcinoma to the Hard Palate. (October 2022)

• Record Type: Journal Article
• Authors: Lyon, Priscilla R. P.; Trevathan, Sean; Talukdar, Rudranath; Nguyen, Dominic D.; McPhaul, Christopher M.; Rampisela, Debby
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 10(2022)
• Publication Date: 2022-10
• Subjects: hepatocellular carcinoma in young adult -- hard palate metastasis -- misdiagnosis -- prognosis -- acinic cell carcinoma; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/23247096221133989
• Languages: English
• ISSNs: 2324-7096

Abstract

Extrahepatic metastasis of hepatocellular carcinoma (HCC) to the head and neck is unusual, especially the oral cavity/maxillofacial region. Metastatic HCC to the hard palate, however, is particularly rare. The most common site of HCC metastasis is the lung, followed by lymph nodes, bone, and adrenal gland. Importantly, oral cavity metastatic HCC may be misdiagnosed as a primary malignancy, such as a salivary gland carcinoma. In this article, we describe a young woman with metastatic HCC to the hard palate that was initially diagnosed as an acinic cell carcinoma.