Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses. (July 2022)

• Record Type: Journal Article
• Authors: Shaaban, Adnan; Anugwom, Chimaobi; Habib, Alma; Mettler, Tetyana; Jaffer, Shahid; Thomson, Mary
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 10(2022)
• Publication Date: 2022-07
• Subjects: hepatic angiosarcoma -- malignant liver tumor -- abnormal liver enzymes -- mortality; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/23247096221111768
• Languages: English
• ISSNs: 2324-7096

Abstract

Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.