A COVID Constellation: A Case of Transverse Myelitis and Acquired von Willebrand Syndrome. (August 2022)

• Record Type: Journal Article
• Authors: Mbonu, Collins; Molokwu, Nneka; Matelski, Alexander
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 10(2022)
• Publication Date: 2022-08
• Subjects: transverse myelitis -- acquired von Willebrand syndrome -- von Willebrand disease -- COVID-19 -- von Willebrand factor; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/23247096221109205
• Languages: English
• ISSNs: 2324-7096

Abstract

The coronavirus disease 2019 (COVID-19) pandemic revealed a myriad of postinfectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequelae, many of which remain poorly understood. We describe a rare presentation of a patient developing 2 simultaneous COVID-19 sequelae: transverse myelitis and acquired von Willebrand syndrome (AVWS). There have been numerous published case reports of patients developing transverse myelitis after a diagnosis of COVID-19. However, none have described AVWS as an observed complication from SARS-CoV-2 infection. To our knowledge, this case report is the first to describe AVWS as a result of COVID-19 infection, suggesting that patients with a prior diagnosis of COVID-19 are susceptible to developing this rare bleeding disorder.