Hypertrophic Cardiomyopathy in the Elderly: A Case Identified With Genetic Screening. (July 2022)

• Record Type: Journal Article
• Authors: Del Rio-Pertuz, Gaspar; Sethi, Pooja; Swaminath, Deephak; Argueta-Sosa, Erwin
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 10(2022)
• Publication Date: 2022-07
• Subjects: hypertrophic cardiomyopathy -- recognition -- genetic screening -- elderly; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/23247096221109204
• Languages: English
• ISSNs: 2324-7096

Abstract

Hypertrophic cardiomyopathy (HCM) is a hereditary disease with an autosomal dominant pattern of inheritance, that is caused by a mutation in one of several sarcomere genes that encodes components of the contractile system of the heart. Hypertrophic cardiomyopathy has been described as a disease that is more heavily diagnosed in the second decade of life, that may present with abnormal syncopal episodes or sudden cardiac death. However, with a better understanding of the genetic changes that occur in HCM and with improved imaging techniques, there has now been an increased recognition of a late-onset disease that can occur in the elderly population. We report a case of a 73-year-old woman who was found to have HCM after various clinical events took place.