Update on Pediatric Sepsis in Mexico. (August 2022)

• Record Type: Journal Article
• Authors: Donath Benitez, Crisell Arely; Mattenberger-Cantú, Estefanía; Salas-Flores, Ricardo; Gómez-Morales, Guillermo Baudelio; Mártinez-Diaz, Paola Alejandra; Moreno-Treviño, María Guadalupe; García-Tovar, Laura Elvira; González-Salazar, Francisco
• Is Part Of: Global pediatric health. Volume 9(2022)
• Publication Date: 2022-08
• Subjects: sepsis -- blood culture -- anti-infective agents -- microbial sensitivity tests -- drug resistance; Pediatrics -- Periodicals; Children -- Health and hygiene -- Periodicals; 618.92
• DOI: 10.1177/2333794X221118017
• Languages: English
• ISSNs: 2333-794X

Abstract

The main objective of this work was to determine and update the causal agents' antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosis of sepsis were reviewed according to the SOFA criteria during 2020 in a public hospital in Mexico. A total of 207 blood cultures were performed and analyzed. The main isolated microorganisms were Staphylococcus, followed by Klebsiella and Escherichia. Several microorganisms showed 100% of sensitivity to different antibiotics or antifungals, some of them include Vancomycin, Voriconazole, Meropenem, Ciprofloxacin, and Cefotaxime. Bacteria of genre Staphylococcus showed its highest sensitivity rate to Tigecycline with 63.3%. Too Staphylococcus showed the highest resistance rate to Oxacillin with 50%. Although the patterns of sepsis-causing germs are similar to those previously reported, the development of new drugs with greater efficacy is the main contribution.